Ligament and Tendon injuries present a significant clinical challenge to orthopedic medicine.

A novel strategy for tendon regeneration is normally reported in the April issue of the Journal of Clinical Investigation. Experts Prof. Dan Gazit and colleagues at the Skeletal Biotechnology Laboratory at the Hebrew University Faculty of Oral Medicine designed mesenchymal stem cells , which reside in the bone marrow and fat tissues, expressing a protein called Smad8 and another known as BMP2. When the researchers implanted these cells into torn Achilles tendons of rats they found that the cells not only survived the implantation process, but also had been recruited to the website of the injury and were able to restoration the tendon. The cells transformed their appearance to look similar to tendon cells , and significantly increased production of collagen, a protein critical for creating strong yet versatile tendons and ligaments.Related StoriesInnovative single-use torque instruments utilize hard polycarbonate from BayerPreventing falls in care homes: an interview with Professor Pip LoganInnovative single-use torque instruments utilize hard polycarbonate from BayerThis initiative is normally an integral objective of the Ten-Year Plan to Strengthen Health Care, in September 2004 which all Initial Ministers signed. The Government of Canada is supporting working out and hiring of even more health care professionals through the $5.5-billion Wait Times Reduction Fund.